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Proteomics
Sequanta Technologies High-throughput Proteomics 
Detection Platform Olink
In order to fulfill the requirements of research and pharmaceutical customers engaged in cohort study, pre-clinical and clinical researches, it is crucial to have a comprehensive and robust technology for accurate measurement of the protein levels across different sample types. Meanwhile, to overcome the challenges of low throughput and low sensitivity associated with traditional protein detection methods, Sequanta Technologies introduced the Olink protein biomarker platform in 2020. This innovative platform is capable of measuring thousands of protein concentrations using minimal sample volumes, and the Olink technology covers the proteins from all major pathways, thus providing high sensitivity, exceptional specificity, and the versatility ofsample compatibility. Sequanta Technologies’ Olink service strictly adheres to the international standards of CLIA/CAP/GCP quality management system, ensuring compliance with regulatory requirements set by authorities such as the FDA and NMPA.

Sequanta Technologies has successfully analyzed more than 20,000 samples using Olink technology. It has been honored with the Platinum badge, making it the sole service provider in China to receive this distinguished recognition. This achievement is a result of an extensive and rigorous evaluation conducted by Olink’s experts. Furthermore, Sequanta Technologies stands out as the first service provider in China with the dual platform for qPCR (Target series) and NGS (Explore series).
Technical Advantages
  • High throughput and low requirements
    By simultaneously analyzing more than 3,000 proteins using a minimum sample volume of 1-24 uL, Sequanta Technologies greatly enhances the efficiency of biomarker screening, enabling faster and more streamlined drug R&D processes.
  • Wide linearity range and high sensitivity
    The wide range of linearity and span of up to 10 logs detectability provides comprehensive coverage of high (ug/mL), medium and low (fg/mL) abundance proteins.
  • High specificity
    The innovative Proximity Extension Assay (PEA) technology reduces cross-reactivity between antibodies by binding two antibodies to the same protein, which significantly improves the specificity of protein detection comparing to other technologies.
  • Rigorously validated protein libraries
    The proteins are carefully chosen and extensively validated, ensuring comprehensive coverage of all major signaling pathways. This breakthrough greatly enhances the success rate of biomarker screening.
  • Suitable for diverse sample types
    It can be used for diverse sample types, including plasma and serum samples, as well as cerebrospinal fluid and cell supernatants et. al.
Service Advantages
The only service provider in China that has been awarded the Platinum badge

To better support the global study, Sequanta Technologies, as the only service provider in China who has been awarded the Platinum badge, has conducted concordance validation with Olink U.S. laboratory. The results showed that it had a high level of consistency between the two laboratories.

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Strict laboratory management to ensure high quality data

Strict and efficient laboratory management ensures high quality data output. The intra- and inter-run coefficients of variation (CV) of Olink assays are lower than the official limits (Intra-CV < 15%, Inter-CV < 25%).

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The red dashed line indicates the criteria for intraand inter-run CV of the sample
The first service provider in China with dual platform for qPCR and NGS

Sequanta Technologies has expanded its capabilities by introducing both the NGS platform (Explore384/3072) and the qPCR platform (Target 96/48), making it the first service provider in China with a dual detection platform.

Widely used in academic research, pre-clinical R&D and clinical trials

Sequanta has successfully analyzed over 20,000 samples for different projects. These samples encompass a wide range of types, including human plasma, serum, tissue lysates, cell lysates, exosomes, as well as mouse and non-human primate samples.

Product Information
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