Our assay is validated and has successfully supported CAR-T therapies approved by NMPA. We provide comprehensive and complete analysis reports for CAR-T, CAR-NK, modified HSC using integrated vectors such as lentiviral vectors or transposons, including insertion site genomic distribution, insertion site sequence preference, and site enrichment in tumor-associated genes.
High sensitivity proteomics platform allows for the simultaneous detection of up to 3,000+ protein markers, covering all major biological pathways. For multiplex cytokine detection, absolute quantification of 45 cytokines can be achieved with sensitivity up to fg/mL with only 1 µL of sample. It can be used for pharmacological efficacy and toxicological studies in pre-clinical in vitro and in vivo experiments, and also for immune marker analysis in efficacy and safety study in clinical trials.
Sequanta Technologies' comprehensive single-cell analysis platform enables the simultaneous detection of vector copy number (VCN) and CAR expression on the cell surface by establishing a direct correlation between VCN and positive expression, providing an accurate information for production process optimization and cell product quality control, successfully overcoming the challenge of high cell heterogeneity